[Preclinical study of the safety of the new Soviet tranquilizer gindarin]

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Farmakol Toksikol. 1983 Jul-Aug;46(4):107-12. [Article in Russian] Arzamastsev EV, Mironova MI, Krepkova LV, Bortnikova VV, Kuznetsov IuV. Abstract The Soviet plant tranquilizer gindarin (an isoquinoline series alkaloid I-tetrahydropalmatine) isolated from the tubers of Stephania glabra Miers was subjected to a preclinical study. As regards the toxicity measured during a single administration to the laboratory animals, ...

Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric and molecular modeling studies

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FEBS J. 2008 Aug;275(15):3971-83. doi: 10.1111/j.1742-4658.2008.06541.x. Epub 2008 Jul 4. Arora A, Balasubramanian C, Kumar N, Agrawal S, Ojha RP, Maiti S. Proteomics and Structural Biology Unit, Institute of Genomics and Integrative Biology, CSIR, Delhi, India. Abstract This study examines the characteristics of binding of berberine to the human telomeric d[AG(3)(T(2)AG(3))(3)] quadruplex. By employing UV-visible ...

Phototoxic and photochemical properties of sanguinarine

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Photochem Photobiol. 1992 Jan;55(1):35-8. Arnason JT, Guèrin B, Kraml MM, Mehta B, Redmond RW, Scaiano JC. Ottawa Carleton Biology Institute, University of Ottawa Campus, Ontario, Canada. Abstract Sanguinarine, a commercial drug exhibiting antimicrobial and antitumor properties, was studied with respect to its basic photochemical characteristics and also with regard to its phototoxicity to mosquito larvae ...

Mucosal mast cell proliferation following normal and heterotopic infections of the nematode Nippostrongylus brasiliensis in rats

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APMIS. 1994 Aug;102(8):589-96. Arizono N, Yamada M, Tegoshi T, Okada M, Uchikawa R, Matsuda S. Department of Medical Zoology, Kyoto Prefectural University of Medicine, Japan. Abstract Infections of intestinal nematodes induce the T cell-dependent proliferation of intestinal mucosal mast cells (MMC). To examine whether nematode-induced MMC proliferation is affected by the site of infestation, adult-stage ...

Kinetics and staining properties of mast cells proliferating in rat small intestine tunica muscularis and subserosa following infection with Nippostrongylus brasiliensis

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APMIS. 1988 Nov;96(11):964-70. Arizono N, Nakao S. Department of Pathology, Shiga University of Medical Science, Ohtsu, Japan. Abstract Mucosal mast-cell hyperplasia occurs in the rat small intestine mucosa after infection with Nippostrongylus brasiliensis. In the present study, the number of mast cells was found to increase in the muscularis and subserosa as well as in ...

Phenotypic changes in mast cells proliferating in the rat lung following infection with Nippostrongylus brasiliensis

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Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;54(1):1-7. Arizono N, Koreto O, Nakao S, Iwai Y, Kushima R, Takeoka O. Department of Pathology, Shiga University of Medical Science, Ohtsu, Japan. Abstract Numerous mast cells appear in rat pulmonary granulomas associated with infection by the nematode Nippostrongylus brasiliensis. The kinetics and histochemical characteristics of these ...

Infection of Nippostrongylus brasiliensis induces development of mucosal-type but not connective tissue-type mast cells in genetically mast cell-deficient Ws/Ws rats

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Blood. 1993 May 15;81(10):2572-8. Arizono N, Kasugai T, Yamada M, Okada M, Morimoto M, Tei H, Newlands GF, Miller HR, Kitamura Y. Department of Medical Zoology, Kyoto Prefectural University of Medicine, Japan. Abstract Ws/Ws rats have a small deletion at the tyrosine kinase domain of the c-kit gene and are deficient in both mucosal mast ...

The berberis story: Berberis vulgaris in therapeutics

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Pak J Pharm Sci. 2007 Jan;20(1):83-92. Arayne MS, Sultana N, Bahadur SS. Department of Chemistry, University of Karachi, Karachi-75270, Pakistan. arayne@gawab.com Abstract Barberry has played a prominent role in herbal healing for more than 2,500 years. Berberis vulgaris is a common garden bush, native to Europe and the British Isles, naturalized in North America, seems ...

Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors.

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Plant Biotechnol J. 2008 Feb;6(2):160-75. Epub 2007 Oct 24. Apuya NR, Park JH, Zhang L, Ahyow M, Davidow P, Van Fleet J, Rarang JC, Hippley M, Johnson TW, Yoo HD, Trieu A, Krueger S, Wu CY, Lu YP, Flavell RB, Bobzin SC. Ceres, Inc., 1535 Rancho Conejo Blvd, Thousand Oaks, CA 91320, USA. napuya@ceres-inc.com Abstract ...

Studies in medicinal plants. 3. Protoberberine alkaloids from the roots of Cissampelos pareira Linn

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Experientia. 1968 Oct 15;24(10):999. Anwer F, Popli SP, Srivastava RM, Khare MP. References PMID: 5711898.