Alkaloids of Thalictrum angustifolium

Posted by on Nov 28, 2012 in Uncategorized | No Comments

J Herb Pharmacother. 2002;2(2):1-10.

Al-Howiriny TA, Zemaitis MA, Lin FT, Beal JL, Schiff PL Jr.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA.


Fractionation and chromatography of the ethanolic extract of the roots of Thalictrum angustifolium L. (Ranunculaceae) afforded five alkaloids: noroxyhydrastinine (1), O-methylthalicberine (2), berberine iodide (3), jatrorrhizine iodide (4), magnoflorine iodide (5). In addition, one simple aromatic compound, methyl-4-hydroxybenzoate (6), was also isolated. These compounds were identified via comparison of their spectral data with authentic compounds or spectra available within our laboratory. This is the first reported isolation of these compounds from this species.